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CAS No. : 1176306-10-7
Sequence: H-Ala-Arg-Val-Tyr-Ile-His-Pro-OH
Molecular formula: C40H62N12O9
Molecular weight : 855
Purity: >98.0%
Details:
Alamandine is an endogenous heptapeptide that can be formed from angiotensin A by angiotensin converting enzyme-2 or directly from angiotensin-(1–7) by decarboxylation of its aspartate residue. Alamandine′s activity is similar to Ang-(1–7) rather than that of angiotensin II or angiotensin A. However, Alamandine acts at a different receptor, the Mas-related receptor, MrgD. Alamandine causes vasodilation, and has antifibrosis and antihypertensive activity.
